Kleiner Brunt Scoring System. , Torbenson, M. Aug 28, 2013 · Alcoholic liver disease (ALD)

, Torbenson, M. Aug 28, 2013 · Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are significant causes of chronic liver disease worldwide. 20701 has been cited by the following article: TITLE: Olmesartan for non-alcoholic steatohepatitis complicated with hypertension: An open-label study AUTHORS: Hisashi Hidaka Several grading and staging systems exist for use in natural history studies and clinical trials, each with some advantages and disadvantages. (Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, Cummings OW, Ferrell LD, Liu YC, Torbenson MS, Unalp-Arida A, Yeh M, McCullough AJ, Sanyal AJ; Nonalcoholic Steatohepatitis Clinical Research Network. 1,2 Although liver fibrosis is the strongest histologic predictor of liver-related outcome and all-cause mortality in Nov 21, 2012 · The histologic characterization of NAFLD and NASH may include description of steatosis and cell injury in addition to inflammation and fibrosis. Main outcomes and measures: Progression and regression of fibrosis stage, using clinical, laboratory, and histologic findings, including the NAFLD activity score (NAS) (sum of scores for steatosis, lobular inflammation, and ballooning; range, 0-8, with 8 indicating more severe disease). The first step in our automated Kleiner and Brunt scoring system is the accurate recognition of histopatho-logical features on the microscopic level. Article citations More>> Kleiner, D. C. Common morphologic factors include the degree of steatosis, inflammation, ballooning change of hepatocytes indicating cellular damage, and fibrosis reflecting the chronicity of liver disease.

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